The Ruger Mark IV 22/45 250th Anniversary is a limited-edition semi-automatic pistol chambered in .22 LR. Its 4.40-inch cold hammer-forged threaded bull barrel is paired with an alloy steel receiver and precision-molded polymer grip frame for dependable function and accurate shooting. The special barrel engraving commemorates America’s 250th Anniversary. A one-button takedown system simplifies field-stripping and chamber-to-muzzle cleaning, while the factory-installed optic mount supports direct mounting of RMR, DPP, and RMSc pattern optics. Fixed front and adjustable rear sights provide a practical aiming setup, and the ambidextrous manual safety accommodates right- or left-handed operation.
Key Features
.22 LR semi-automatic pistol with 10+1 capacity for economical target shooting
4.40-inch cold hammer-forged threaded bull barrel with 1/2×28 threads and thread protector
Factory-installed optic mount compatible with RMR, DPP, and RMSc pattern optics
One-button takedown enables fast, tool-free field-stripping and cleaning
Ambidextrous manual safety can be configured for left-side-only operation
Fixed front sight and adjustable rear sight support precise aiming without an optic
The Ruger Mark IV 22/45 250th Anniversary combines proven rimfire performance, easy maintenance, and modern optic compatibility in a commemorative configuration.
